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Rooms and Guests2 Guests, 1 Room
Key details

Hotel overview and key features

167 West Main Street, Lexington, Kentucky, United States, 40507

21C Museum Hotel Lexington, a 4-star hotel near Blue Grass Airport (9.5 miles away), occupies the historic Fayette National Bank Building in downtown Lexington. The property is within 0.5 miles of Triangle Park, Mary Todd Lincoln House, and Kentucky Theatre. Contemporary art exhibitions fill the 7000 square feet of gallery space throughout this boutique hotel.

Art-Infused Accommodations

Guest rooms at 21c Lexington feature custom-designed furnishings, Malin + Goetz bath amenities, and original artwork. Options include City Queen, Deluxe King, Deluxe Double Queen, and suites like the Skylight Suite with a separate living area. The Nightwatch room doubles as a fully immersive art installation by Chris Doyle.

Local Flavors Dining

Lockbox restaurant serves American cuisine with Kentucky-sourced ingredients, offering breakfast, dinner, and weekend brunch. The bar + lounge provides craft cocktails and seasonal menus influenced by local producers. Private dining is available in the restored bank safe room.

Art & Bourbon Experiences

21c Museum Hotel Lexington displays rotating contemporary art exhibitions across five private galleries. Guests can explore the Legacy Trail to Kentucky Horse Park or visit nearby distilleries like Castle & Key. The hotel hosts mocktail tours and cocktail classes like Cocktail, Savings & Booze.

Versatile Event Spaces

The property offers 7000 square feet of event space, including a Main Gallery for 250 guests. Business services include a 24-hour center and AV-equipped conference rooms for 12 attendees. Sustainable meeting options feature locally sourced catering from Lockbox's culinary team.

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Choose your ideal room style

Choose from family rooms, suites, flexible cancellation & more
City Queen Room
2 persons
22 m² 
1 King-size bed
Shower
Coffee machine
Deluxe Queen Room
2 persons
33 m² 
2 King Size Beds
Shower
Coffee machine
Deluxe King Room
2 persons
31 m² 
1 King-size bed
Shower
Coffee machine
Corner King Room
2 persons
40 m² 
1 King-size bed
Shower
Coffee machine
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Prices and Availability

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Getting around

Transportation options available

City Centre
Lexington400 m
Airports
Blue Grass (LEX) 13.7 km

Facilities

Stay relaxed and refreshed just minutes from the airport

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Paid shuttle service
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's menu

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Dressing area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Location info

167 West Main Street, Lexington, Kentucky, United States, 40507
Map view
167 West Main Street, Lexington, Kentucky, United States, 40507
Nearby
430 West Vine Street
Rupp Arena
460 m
Museum
Hunt-Morgan House
460 m
Event hall
Lexington Convention Center
440 m
Theatre
Kentucky Theatre
360 m
440 W Short St
Explorium
450 m
University
University of Kentucky
90 m
Park
Triangle Park
340 m
Church
St Paul the Apostle Catholic Church
430 m
Library
Lexington Public Library Ceiling Clock and Foucault Pendulum
260 m
Shopping Area
Victorian Square Shoppes
340 m
Square
Phoenix Park
180 m
Gallery
Limestone Blue
130 m
Lexington Financial Center
Isaac Murphy Memorial Art Garden
140 m
Gallery
Pam Miller Downtown Arts Center
220 m
Gallery
ArtsPlace
240 m
7285 Huron Street
Huron Street Gallery
250 m
Gratz Park
490 m
Restaurants
Bourbon on Rye
70 m
115 W Main St
Corto Lima
180 m
101 West Short Street Corner of West Short and North Limestone Streets
School Sushi
120 m
163 West Short Street
Bluegrass Tavern
150 m
115 Cheapside
Horse And Jockey
190 m
131 Cheapside
Buddha Lounge
190 m
109 N Mill St
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Check-in
12Nov2025Select date
Check-out
13Nov2025Select date
Rooms and Guests2 Guests, 1 Room